Advances in Gene Delivery Systems

Advances in Gene Delivery Systems

1Department of Biotechnology, School of Life Sciences, Central University of Rajasthan, Bandarsindri, N.H. 8, Tehsil Kishangarh, District Ajmer, Rajasthan 305817, India 2Genomics and Nanotoxicology, Laboratory Mechanistic Studies Division, Health Canada, Ottawa, ON, Canada K1A 0K9 3Department of Electro and Biophysics, Plasma Bioscience Research Centre, Kwangwoon University, Wolgye-Dong, Nowon-...

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery

Advances in cationic lipid-mediated gene delivery

Benjamin Martin, Abderrahim Aissaoui, Matthieu Sainlos, Noufissa Oudrhiri, Michelle Hauchecorne, Jean-Pierre Vigneron, Jean-Marie Lehn and Pierre Lehn 1 Laboratoire de Chimie des Interactions Moléculaires, CNRS UPR 285, Collège-de-France, 11 Place Marcelin Berthelot, 75005 Paris, France. 2 INSERM U458, Hôpital Robert Debré, 48 Boulevard Sérurier, 75019 Paris, France ____________________________...

Recent Advances in Hemophilia Gene Therapy

Heterogeneous loss of function mutations at F8 and F9 genes causes X-linked recessive bleeding disorders, hemophilia A (HA) and hemophilia B (HB), respectively. HA is clinically indistinguishable from HB and accounts for more than 80% of hemophilia cases; the former affects 1/5000 and the latter 1/25000 male births worldwide. In Iran, it is estimated that around 4300 HA and 900 HB patients are ...